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MOSAIC Therapy

Ocular Movements and Alternating Stimulations for Cerebral Integration

Integrative therapeutic approach based on neuroscience

2019
Founded
24 years
CNRS Research
1-3
Observed sessions
Dr. Stephanie Khalfa, founder of the MOSAIC method

Definition and scientific context

MOSAIC therapy, co-founded in 2019, represents an integrative therapeutic approach based on 24 years of research conducted by Stephanie Khalfa, PhD in neuroscience, at CNRS Marseille. This work specifically focuses on the brain mechanisms of stress, emotions, and psychological trauma.

Since 2021, Dr. Khalfa has continued developing this method in a rigorous scientific approach, integrating recent advances in neuroscience and validating protocols through clinical studies.

Fundamental principle

The transformation of the traumatic imprint at the brain level without requiring direct re-exposure to trauma, relying on mechanisms of neuronal plasticity and memory reconsolidation.

Neuroscience research
24 years of research at CNRS Marseille

Neurophysiological mechanisms

The MOSAIC method is based on three main mechanisms:

1. Alternating bilateral stimulations

Bilateral stimulations (acoustic, tactile or visual) generate neuronal activity that facilitates:

  • Regulation of the amygdala and limbic system
  • Activation of the prefrontal cortex promoting emotional control
  • Interhemispheric synchronization facilitating information integration
  • Reduction of sympathetic hyperactivation

2. Activation of positive internal resources

The protocol systematically includes the activation of positive resources allowing:

  • Anchoring of feelings of safety and control
  • Creation of new emotional response patterns
  • Strengthening of emotional regulation circuits

3. Memory reconsolidation and brain plasticity

The therapeutic intervention mobilizes brain plasticity processes:

  • Modification of emotional encoding associated with memory
  • Reduction of affective load through reconsolidation
  • Adaptive integration of experience into autobiographical memory
  • Extinction of conditioned fear responses

Clinical applications and benefits

MOSAIC therapy session
Caring and personalized support

Observed benefits

Rapid symptomatic resolution

Clinically significant improvement observed in 1 to 3 sessions, without need for direct exposure to traumatic memories.

Reduction of post-traumatic manifestations

Measurable decrease in hypervigilance, startle reactions, memory intrusions and associated somatic manifestations.

Lasting emotional stabilization

Installation of adaptive emotional regulation patterns with long-term maintenance of benefits.

Developmental adaptability

Specific protocols validated for different age groups (children, adolescents, adults) with appropriate methodological adjustments.

Therapeutic indications

  • Post-Traumatic Stress Disorder (PTSD)
  • Generalized anxiety disorders
  • Panic attacks
  • Specific phobias
  • Eating disorders
  • Professional burnout syndrome
  • Attachment disorders
  • Chronic pain of psychosomatic origin
  • Sleep disorders related to stress
  • Reactive depression

Professional training

MOSAIC therapy training is designed for healthcare professionals and helping relationship practitioners wishing to enrich their clinical practice.

MOSAIC practitioner training
Training with Dr. Stephanie Khalfa

Benefits for professionals

Standardized protocol

Structured methodology in reproducible steps, facilitating integration into existing clinical practice.

Integrative compatibility

Compatible with established therapeutic approaches: EMDR, IFS, clinical hypnosis, CBT, psychodynamic and systemic approaches.

Extended field of application

Applicable to simple and complex traumas, anxiety disorders, eating disorders, addictions, relational and developmental issues.

Training program

Complete and structured pathway to master MOSAIC® therapy

1

Fundamental module

Acquisition of theoretical foundations and standard clinical protocol

2

Specialization modules

Specific applications (complex trauma, eating disorders, pediatric population, couples therapy)

3

Practical workshops

Clinical simulations and case studies

4

Clinical supervision

Individual and group support post-training

5

Continuing education

Regular updates integrating research advances

Scientific foundations

David Servan-Schreiber Prize 2019

Awarded to Dr. Stephanie Khalfa for her work on the neurophysiological mechanisms of bilateral stimulations and their therapeutic application.

Neurophysiological bases

Synaptic plasticity

Brain's ability to reorganize its neuronal connections

Memory reconsolidation

Modification of memory traces during their reactivation

Limbic regulation

Modulation of amygdala activity by the prefrontal cortex

Interhemispheric integration

Synchronization of bilateral brain networks

Main scientific publications

Khalfa S, Poupard G. (2021)

MOSAIC: A New Pain-Free Psychotherapy for Psychological Trauma

American Journal of Psychotherapy, 74(1):40-43
Rousseau PF, et al. (2021)

Sleep parameters improvement in PTSD soldiers after symptoms remission

Scientific Reports, 11(1):8873
Rousseau PF, et al. (2020)

Cracking the EMDR code: Recruitment of sensory, memory and emotional networks

Australian & New Zealand Journal of Psychiatry, 54(12):1197-1209
Boukezzi S, et al. (2017)

Bilateral Alternating Auditory Stimulations Facilitate Fear Extinction and Retrieval

Frontiers in Psychology, 8:990

Integrative approach

MOSAIC therapy harmoniously integrates several validated therapeutic approaches:

EMDR

Eye Movement Desensitization and Reprocessing

Strategic brief therapy

Rapid and targeted solutions

Solution-focused therapy

Focus on resources and capabilities

Clinical hypnosis

Altered states of consciousness to facilitate change

Nonviolent Communication

Caring therapeutic relationship

Ego-state therapy

Ego-state therapy for parts integration

Internal Family System

Internal Family System for inner harmonization

Polyvagal theory

Autonomic nervous system regulation

Testimonials

Concrete transformations experienced by our patients

Patient testimonial
Successful therapy
Restored well-being

I had tried several therapies without success. With MOSAIC, I was finally able to free myself from my anxieties without having to tell everything in detail. It was exactly what I needed.

Camille, 38 years old

Generalized anxiety

After my accident, I couldn't drive anymore. In three sessions, I got my freedom back. It's incredible how the change happened naturally.

Marc, 45 years old

Driving phobia

MOSAIC allowed me to make peace with my past. I'm no longer a prisoner of my memories, I can finally move forward.

Lea, 29 years old

Childhood trauma

Frequently asked questions

Will I have to tell my trauma in detail?

No, that's precisely one of the advantages of MOSAIC. You don't need to relive or tell in detail your painful experiences.

How many sessions are needed?

Most people see significant improvement in 1 to 3 sessions. Some more complex situations may require a few additional sessions.

Are there side effects?

MOSAIC is a gentle method. You may feel slight fatigue after the session, a sign that your brain is working to integrate the changes.

Is it covered by insurance?

If your practitioner is a psychologist or psychiatrist, part may be covered. Check with your insurance provider.

Deepen your understanding of the MOSAIC® method

Discover the reference book to deeply understand the scientific foundations and practical application of MOSAIC® therapy

From EMDR to MOSAIC® therapy

From EMDR to MOSAIC® therapy

Healing psychological trauma without pain

By Dr. Stéphanie Khalfa, CNRS Research Director

What you will discover:

  • The neurophysiological foundations of MOSAIC® therapy
  • The evolution from EMDR to a more integrative approach
  • Clinical cases and concrete testimonials
  • Clinical applications and therapeutic protocols

Join the MOSAIC community

For any information

Training / Administration

coordination@therapiemosaic.com

+33 7 82 59 21 49

Method / Research

contact@therapiemosaic.com

+33 6 89 99 07 12